Inhibiting the IGF-1 receptor with the cyclolignan Picropodophyllin: an in vitro study of ovulation, implantation and receptivity in a mouse model
Picropodophyllin (PPP) is an analogue of the anti tumour lignan podophyllotoxin with the unique ability to selectively inhibit the receptor of Insulin like growth factor 1(IGF-1). IGF-1 is believed to play an important part in development of the endometrium facing implantation. With PPP treated mice...
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| Format: | Others |
| Language: | Swedish |
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Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2008
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-89109 |