Computer simulations of ribosome reactions

Computer simulations of ribosome reactions

Peptide bond formation and translational termination on the ribosome have been simulated by molecular mechanics, free energy perturbation, empirical valence bond (MD/FEP/EVB) and automated docking methods. Recent X-ray crystallographic data is used here to calculate the entire free energy surface fo...

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Bibliographic Details
Main Author: Trobro, Stefan
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för cell- och molekylärbiologi 2008
Subjects:
Molecular biology
ribosomal termination
Empirical valence bond
peptidyl transfer
Molekylärbiologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8429
http://nbn-resolving.de/urn:isbn:978-91-554-7083-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8429
http://nbn-resolving.de/urn:isbn:978-91-554-7083-8

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