Clusterin and Megalin in The Spinal Cord
Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. These results suggest t...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för neurovetenskap
2006
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7365 http://nbn-resolving.de/urn:isbn:91-554-6739-3 |