Clusterin and Megalin in The Spinal Cord

Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. These results suggest t...

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Bibliographic Details
Main Author: Wicher, Grzegorz
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för neurovetenskap 2006
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7365
http://nbn-resolving.de/urn:isbn:91-554-6739-3