Screening for Candidate Brain Tumor Genes : Identifying Genes that Cooperate with Platelet-Derived Growth Factor in Glioma Development and Progression

Screening for Candidate Brain Tumor Genes : Identifying Genes that Cooperate with Platelet-Derived Growth Factor in Glioma Development and Progression

Malignant primary brain tumors, gliomas, often overexpress both platelet-derived growth factor (PDGF) ligands and receptors providing an autocrine and/or paracrine boost to tumor growth. Glioblastoma multiforme (GBM) is the most frequent glioma. Its aggressive and infiltrative growth renders it extr...

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Bibliographic Details
Main Author: Johansson, Fredrik
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för genetik och patologi 2006
Subjects:
Pathology
PDGF
insertional mutagenesis
retroviral tagging
common insertion site
glioma
expression
cGMP-dependent protein kinase II
Patologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7185
http://nbn-resolving.de/urn:isbn:91-554-6677-X

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7185
http://nbn-resolving.de/urn:isbn:91-554-6677-X

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