Genetic Engineering of T Lymphocytes for Cancer Immunotherapy : Optimisation of Gene Transfer
T lymphocytes can be rendered specific against a wide range of antigens by the genetic transfer of a chimeric receptor, a fusion between the antigen-binding domain of an antibody and the signalling domain of a T cell receptor. The use of such chimeric T lymphocytes has shown promising results for ca...
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| Format: | Others |
| Language: | English |
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Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2006
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7139 |