Anti-Diabetic and Beta-Cell Protective Actions of Imatinib Mesylate
Type 1 diabetes is a disease resulting from the progressive immune-mediated destruction of insulin producing β-cells. In order to understand more about diabetes we need to understand the mechanisms governing β-cell death. The leukemia drug Gleevec is a tyrosine kinase inhibitor that targets c-Abl. S...
| Main Author: | |
|---|---|
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
Uppsala universitet, Institutionen för medicinsk cellbiologi
2006
|
| Subjects: | |
| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7078 http://nbn-resolving.de/urn:isbn:91-554-6615-X |