RhoGTPase Signaling in Cell Polarity and Gene Regulation
RhoGTPases are proteins working as molecular switches as they bind and hydrolyze GTP. They are in their active conformation when GTP is bound and are then able to interact with their effector proteins, which relay the downstream signaling. When the GTP is hydrolyzed to GDP, the RhoGTPase is inactiva...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Ludwiginstitutet för cancerforskning
2006
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6698 http://nbn-resolving.de/urn:isbn:91-554-6505-6 |