Using Pharmacokinetic and Pharmacodynamic Principles to Evaluate Individualisation of Antibiotic Dosing – Emphasis on Cefuroxime

Using Pharmacokinetic and Pharmacodynamic Principles to Evaluate Individualisation of Antibiotic Dosing – Emphasis on Cefuroxime

Cefuroxime is a renally eliminated antibiotic used against a variety of different bacterial infections. The pharmacokinetics (PK) for cefuroxime was studied in 97 hospitalized patients using population analysis. To be able to measure cefuroxime in human serum a new sensitive analytical method was de...

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Bibliographic Details
Main Author: Viberg, Anders
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Avdelningen för farmakokinetik och läkemedelsterapi 2006
Subjects:
Pharmacokinetics/Pharmacotherapy
Cefuroxime
pharmacokinetics
pharmacodynamics
dosing individualisation
NONMEM
Farmakokinetik/Farmakoterapi
PHARMACY
FARMACI
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6639
http://nbn-resolving.de/urn:isbn:91-554-6499-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6639
http://nbn-resolving.de/urn:isbn:91-554-6499-8

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