Microwave-Assisted Synthesis of C2-Symmetric HIV-1 Protease Inhibitors : Development and Applications of In Situ Carbonylations and other Palladium(0)-Catalyzed Reactions
The HIV protease is an essential enzyme for HIV replication and constitutes an important target in the treatment of HIV/AIDS. Efficient combination therapies using inhibitors of the reverse transcriptase and protease enzymes have led many to reevaluate HIV infections from a terminal condition to a c...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Avdelningen för organisk farmaceutisk kemi
2005
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5804 http://nbn-resolving.de/urn:isbn:91-554-6254-5 |