Role of Bone Morphogenetic Proteins for Catecholaminergic Neurons in Vivo : Use of the Tyrosine Hydroxylase Locus for Cell-Specific inactivation of Signal Transduction

Role of Bone Morphogenetic Proteins for Catecholaminergic Neurons in Vivo : Use of the Tyrosine Hydroxylase Locus for Cell-Specific inactivation of Signal Transduction

Members of the Transforming Growth factor-β (TGF-β) superfamily and its subclass Bone Morphogenetic Proteins (BMP) play important roles for nervous system development. In order to study the BMP role for catecholaminergic neurons in vivo, we generated three knock-in mice, expressing the transgenes s...

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Bibliographic Details
Main Author: Usoskin, Dmitry
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Medicinsk utvecklingsbiologi 2004
Subjects:
Neurosciences
Tyrosine Hydroxylase
Bone Morphogenetic Proteins (BMP)
Transforming Growth Factor-β (TGF-β)
tissue-specific knockout
Parkinson's disease
Neurovetenskap
Neurology
Neurologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4258
http://nbn-resolving.de/urn:isbn:91-554-5964-1

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4258
http://nbn-resolving.de/urn:isbn:91-554-5964-1

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