Blood-Brain Barrier Transport of Drugs Across Species with the Emphasis on Health, Disease and Modelling

Blood-Brain Barrier Transport of Drugs Across Species with the Emphasis on Health, Disease and Modelling

The transport of drugs across the blood-brain barrier (BBB) has been investigated in different species using morphine and morphine-6-glucuronide (M6G) as model compounds. The influence of probenecid on the BBB transport of morphine and M6G was investigated, and the consequences of meningitis and sev...

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Bibliographic Details
Main Author: Tunblad, Karin
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Avdelningen för farmakokinetik och läkemedelsterapi 2004
Subjects:
Pharmaceutical biosciences
Blood-brain barrier
Disease
Microdialysis
Modelling
Transport
Pharmacokinetics
NONMEM
Farmaceutisk biovetenskap
Biopharmacy
Biofarmaci
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4005
http://nbn-resolving.de/urn:isbn:91-554-5879-3

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4005
http://nbn-resolving.de/urn:isbn:91-554-5879-3

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