Modulation of PDGF Receptor Signaling via the Phosphatase SHP-2 and the Docking Protein Gab1
x === Platelet-derived growth factors (PDGF), a family of potent mitogens and chemoattractants for cells of mesenchymal origin, elicit their biological effects through the binding of two related receptor tyrosine kinases, denoted α- and β-receptors. The binding of PDGF to the receptors causes recep...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Ludwiginstitutet för cancerforskning
2003
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3748 http://nbn-resolving.de/urn:isbn:91-554-5780-0 |