Modulation of PDGF Receptor Signaling via the Phosphatase SHP-2 and the Docking Protein Gab1

x === Platelet-derived growth factors (PDGF), a family of potent mitogens and chemoattractants for cells of mesenchymal origin, elicit their biological effects through the binding of two related receptor tyrosine kinases, denoted α- and β-receptors. The binding of PDGF to the receptors causes recep...

Full description

Bibliographic Details
Main Author: Kallin, Anders
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Ludwiginstitutet för cancerforskning 2003
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3748
http://nbn-resolving.de/urn:isbn:91-554-5780-0