Expression of Genes Encoding for Drug Metabolism in the Small Intestine

Expression of Genes Encoding for Drug Metabolism in the Small Intestine

This investigation focused on the mRNA expression of drug metabolising Cytochromes P-450 (CYP) and UDP-glucuronosyltransferases (UGT) and the transport protein P-glycoprotein (Pgp) in the small intestine of humans and rats. The mRNA expression of the investigated genes in the human small intestine (...

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Bibliographic Details
Main Author: Lindell, Monica
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Avdelningen för farmaceutisk biokemi 2003
Subjects:
Pharmaceutical biochemistry
CYPs
UGTs
interindividual variation
small intestine
human
rat
artemisinin
CAR-receptor regulation
Farmaceutisk biokemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3601
http://nbn-resolving.de/urn:isbn:91-554-5753-3

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3601
http://nbn-resolving.de/urn:isbn:91-554-5753-3

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