Optimization of pyrosequencing method for copy number analysis of CYP2D6
CYP2D6, a member of the cytochrome P450 enzyme system, has a central role in drug metabolism, it metabolizes 25 % of clinically used drugs. The gene that codes for the enzyme displays a high degree of polymorphism, which effects enzyme functions to various degrees. Aside from smaller mutations like...
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| Format: | Others |
| Language: | Swedish |
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Uppsala universitet, Institutionen för kvinnors och barns hälsa
2017
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-324758 |