Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. Mast cells accumulate at certain sites i...

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Bibliographic Details
Main Author: Zarnegar, Behdad
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2016
Subjects:
Mast cells
Mast cell progenitors
Recruitment
Lung
Virus
Influenza
Innate immunity
Poly I:C
IL-33
VAAT
SLC10A4
Degranulation
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-306115
http://nbn-resolving.de/urn:isbn:978-91-554-9746-0

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-306115
http://nbn-resolving.de/urn:isbn:978-91-554-9746-0

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