Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells
The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendr...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Reumatologi
2015
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-246526 http://nbn-resolving.de/urn:isbn:978-91-554-9203-8 |