Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells

Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells

The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendr...

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Bibliographic Details
Main Author: Berggren, Olof
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Reumatologi 2015
Subjects:
Systemic lupus erythemtosus
IFN-alpha
autoimmunity
immune complex
single nuclear polymorphisms
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-246526
http://nbn-resolving.de/urn:isbn:978-91-554-9203-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-246526
http://nbn-resolving.de/urn:isbn:978-91-554-9203-8

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