Understanding Cancer Mutations by Genome Editing
Mutational analyses of cancer genomes have identified novel candidate cancer genes with hitherto unknown function in cancer. To enable phenotyping of mutations in such genes, we have developed a scalable technology for gene knock-in and knock-out in human somatic cells based on recombination-mediate...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Genomik
2014
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-235680 http://nbn-resolving.de/urn:isbn:978-91-554-9106-2 |