CD19-targeting CAR T Cells for Treatment of B Cell Malignancies : From Bench to Bedside
Immunotherapy for cancer is a young research field progressing at high speed. The first chimera of an antibody and a signaling chain was designed by Zelig Eshhar and was later further developed to enhance existing T cell therapy by combining a single-chain fragment of an antibody with the CD3 zeta c...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Klinisk immunologi
2014
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-232638 http://nbn-resolving.de/urn:isbn:978-91-554-9047-8 |