Rule-based Models of Transcriptional Regulation and Complex Diseases : Applications and Development

Rule-based Models of Transcriptional Regulation and Complex Diseases : Applications and Development

As we gain increased understanding of genetic disorders and gene regulation more focus has turned towards complex interactions. Combinations of genes or gene and environmental factors have been suggested to explain the missing heritability behind complex diseases. Furthermore, gene activation and sp...

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Bibliographic Details
Main Author: Bornelöv, Susanne
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Beräknings- och systembiologi 2014
Subjects:
Histone modification
Transcription factor
Transcriptional regulation
Next-generation sequencing
Feature selection
Machine learning
Rule-based classification
Asthma
Allergy
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-230159
http://nbn-resolving.de/urn:isbn:978-91-554-9005-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-230159
http://nbn-resolving.de/urn:isbn:978-91-554-9005-8

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