Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms

Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms

Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure...

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Bibliographic Details
Main Author: Mao Söderberg, Mao
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Klinisk farmakogenomik och osteoporos 2012
Subjects:
olanzapine
pharmacogenetics
drug metabolism
schizophrenia
therapeutic drug monitoring
FMO1
FMO3
CYP1A2
UGT1A4
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179957
http://nbn-resolving.de/urn:isbn:978-91-554-8454-5

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179957
http://nbn-resolving.de/urn:isbn:978-91-554-8454-5

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