Bacterial Sortase A as a drug target

Sortase A is a housekeeping enzyme of Gram-positive bacteria that catalyses the anchoring of surface proteins to the bacterial peptidoglycan. The enzyme works to establish an interaction between bacteria and host cells and is essential for pathogenesis. This makes Sortase A a potential suitable targ...

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Bibliographic Details
Main Author: Larsson, Caroline
Format: Others
Language:English
Published: Uppsala universitet, Institutionen för biologisk grundutbildning 2012
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176862