Reducing Attrition via Improved Strategies for Pre-clinical Drug Discovery : SPR-biosensor Aided Interaction Studies
The efficacy of a drug is tightly intertwined with its interaction mechanism with the drug target. The mechanism is dependent on the physicochemical and structural characteristics of both target and drug molecule. Drug discovery is plagued by a high attrition rate, whereas in the clinic, a major iss...
| Main Author: | |
|---|---|
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
Uppsala universitet, Biokemi
2012
|
| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-171997 http://nbn-resolving.de/urn:isbn:978-91-554-8340-1 |