EGFR- and HER2-Binding Affibody Molecules : Cellular studies of monomeric, dimeric and bispecific ligands
Abnormal expression and signaling of the ErbB receptors is associated with the development and progression of several forms of cancer. In this thesis, new ErbB-targeting affibody molecules are evaluated regarding their cellular effects in vitro. Since ligand binding to an ErbB receptor might have an...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Enheten för biomedicinsk strålningsvetenskap
2011
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160173 http://nbn-resolving.de/urn:isbn:978-91-554-8195-7 |