Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglyca...

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Bibliographic Details
Main Author: O'Callaghan, Paul
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Geriatrik 2011
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-159927
http://nbn-resolving.de/urn:isbn:978-91-554-8183-4

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