Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglyca...
Main Author: | O'Callaghan, Paul |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
Uppsala universitet, Geriatrik
2011
|
Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-159927 http://nbn-resolving.de/urn:isbn:978-91-554-8183-4 |
Similar Items
-
Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia
by: Hjertström, Elina
Published: (2011) -
Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan
by: Zehra Elgundi, et al.
Published: (2020-01-01) -
Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
by: Arvindhan Nagarajan, et al.
Published: (2018-08-01) -
Editorial: Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets
by: Cinzia Lanzi, et al.
Published: (2020-02-01) -
Heparan Sulfate Mimetics in Cancer Therapy: The Challenge to Define Structural Determinants and the Relevance of Targets for Optimal Activity
by: Cinzia Lanzi, et al.
Published: (2018-11-01)