Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglyca...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Geriatrik
2011
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-159927 http://nbn-resolving.de/urn:isbn:978-91-554-8183-4 |