Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy in man with stromal fibrosis as one of the main features. Carcinoma cells synthesized no or little collagen I protein. Pro-α1(I) collagen mRNA was expressed by stromal cells throughout the tumor, but expression of procollagen type I prot...

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Bibliographic Details
Main Author: Lammerts, Ellen
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2001
Subjects:
Biochemistry
Collagen I synthesis
Fibrosis
Tumor - stroma interactions
PDGF
TGF-β
Inhibitor
Cell cycle
Tumor growth
Hyaluronan
Biokemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1594
http://nbn-resolving.de/urn:isbn:91-554-5198-5

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1594
http://nbn-resolving.de/urn:isbn:91-554-5198-5

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