Coupling of substances containing a primary amine to hyaluronan via carbodiimide-mediated amidation
The purpose of this study was to investigate the carbodiimide-mediated amidation of hyaluronan (HA). The carbodiimide-mediated amidation includes the formation of a urea derivative, O-acylisourea, between the carbodiimide and a carboxylic group of HA, which a primary amine can displace, resulting in...
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Format: | Others |
Language: | English |
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Uppsala universitet, Institutionen för biokemi och organisk kemi
2010
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-149284 |