Coupling of substances containing a primary amine to hyaluronan via carbodiimide-mediated amidation

The purpose of this study was to investigate the carbodiimide-mediated amidation of hyaluronan (HA). The carbodiimide-mediated amidation includes the formation of a urea derivative, O-acylisourea, between the carbodiimide and a carboxylic group of HA, which a primary amine can displace, resulting in...

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Bibliographic Details
Main Author: Mojarradi, Hotan
Format: Others
Language:English
Published: Uppsala universitet, Institutionen för biokemi och organisk kemi 2010
Subjects:
EDC
NHS
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-149284