Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies

Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies

Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. This thesis focuses on the development and evaluation of pharmacometric m...

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Bibliographic Details
Main Author: Nielsen, Elisabet I
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2011
Subjects:
Pharmacometrics
pharmacokinetics
pharmacodynamics
modeling
NONMEM
antibiotics
in vitro
time-kill curve
PK/PD indices
gentamicin
aminoglycosides
newborn infants
premature infants
cystatin C
Biopharmacy
Biofarmaci
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-144909
http://nbn-resolving.de/urn:isbn:978-91-554-8002-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-144909
http://nbn-resolving.de/urn:isbn:978-91-554-8002-8

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