Optimization of High Resolution Melting Analysis for Detection of KRAS Gene Mutations

Optimization of High Resolution Melting Analysis for Detection of KRAS Gene Mutations

Background: Mutations of the KRAS oncogene occur in a variety types of human tumors. By assessing the mutation status of KRAS, clinicians can predict patient response to anti-EGFR therapy such as cetuximab (Erbitux®) or panitumumab (Vectibix®) in patients with metastatic colorectal cancer. The aim o...

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Bibliographic Details
Main Author:	Darbandy, Ashna
Format:	Others
Language:	English
Published:	Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2010
Online Access:	http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-130751

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