Optimization of High Resolution Melting Analysis for Detection of KRAS Gene Mutations
Background: Mutations of the KRAS oncogene occur in a variety types of human tumors. By assessing the mutation status of KRAS, clinicians can predict patient response to anti-EGFR therapy such as cetuximab (Erbitux®) or panitumumab (Vectibix®) in patients with metastatic colorectal cancer. The aim o...
| Main Author: | |
|---|---|
| Format: | Others |
| Language: | English |
| Published: |
Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2010
|
| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-130751 |