Regulation of TGF-β Signaling by Post-Translational Modifications
Transforming growth factor-β (TGF-β) signaling is initiated when the ligand binds to type II and type I serine/threonine kinase receptors at the cell surface. Activated TGF-β type I receptors phosphorylate R-Smads which relocate, together with co-Smads, to the cell nucleus and regulate transcription...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Ludwiginstitutet för cancerforskning
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128855 http://nbn-resolving.de/urn:isbn:978-91-554-7844-5 |