Regulation of PDGFRβ signaling
Platelet-derived growth factor (PDGF) isoforms, which bind to closely related a- and b-tyrosine kinase receptors, induce migration, proliferation, survival and differentiation of mesenchymal cells. They signal by the active receptor attracting Src homology 2 (SH2) domain containing proteins, which s...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Ludwiginstitutet för cancerforskning
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-123045 http://nbn-resolving.de/urn:isbn:978-91-554-7813-1 |