Adenovirus-mediated Gene Therapy of Prostate Cancer

Adenovirus-mediated Gene Therapy of Prostate Cancer

Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. In this thesis, an oncolytic serotype 5 adenovirus (Ad5), Ad[i/PPT-E1A, E3], was devel...

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Bibliographic Details
Main Author:	Danielsson, Angelika
Format:	Doctoral Thesis
Language:	English
Published:	Uppsala universitet, Enheten för klinisk immunologi 2010
Subjects:	adenovirus adenoviral vector oncolytic virus gene therapy prostate cancer PEGylation HDAC inhibitor whole blood model whole blood neutralization assay MEDICINE MEDICIN
Online Access:	http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114132 http://nbn-resolving.de/urn:isbn:978-91-554-7726-4

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