Adenovirus-mediated Gene Therapy of Prostate Cancer

Adenovirus-mediated Gene Therapy of Prostate Cancer

Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. In this thesis, an oncolytic serotype 5 adenovirus (Ad5), Ad[i/PPT-E1A, E3], was devel...

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Bibliographic Details
Main Author: Danielsson, Angelika
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Enheten för klinisk immunologi 2010
Subjects:
adenovirus
adenoviral vector
oncolytic virus
gene therapy
prostate cancer
PEGylation
HDAC inhibitor
whole blood model
whole blood neutralization assay
MEDICINE
MEDICIN
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114132
http://nbn-resolving.de/urn:isbn:978-91-554-7726-4

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114132
http://nbn-resolving.de/urn:isbn:978-91-554-7726-4

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