Oscillatory Signaling and Insulin Secretion from Single ß-cells
cAMP and Ca2+ are key regulators of exocytosis in many cells, including insulin-secreting pancreatic β-cells. Glucose-stimulated insulin secretion from β-cells is pulsatile and driven by oscillations of the cytoplasmic Ca2+ concentration ([Ca2+]i), but little is known about the kinetics of cAMP sign...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för medicinsk cellbiologi
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-113686 http://nbn-resolving.de/urn:isbn:978-91-554-7718-9 |