Peptidomimetic Enzyme Inhibitors : Targeting M. tuberculosis Ribonucleotide Reductase and Hepatitis C Virus NS3 Protease

Peptidomimetic Enzyme Inhibitors : Targeting M. tuberculosis Ribonucleotide Reductase and Hepatitis C Virus NS3 Protease

This thesis focuses on the design and synthesis of inhibitors targeting Mycobacterium tuberculosis ribonucleotide reductase (RNR) and hepatitis C virus (HCV) NS3 protease; enzymes that have been identified as potential drug targets for the treatment of tuberculosis and hepatitis C, respectively. Sma...

Full description

Bibliographic Details
Main Author: Nurbo, Johanna
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Avdelningen för organisk farmaceutisk kemi 2010
Subjects:
enzyme inhibitor
peptidomimetics
structure-activity relationship
tuberculosis
ribonucleotide reductase
hepatitis C virus
NS3 protease
Pharmaceutical chemistry
Farmaceutisk kemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-112345
http://nbn-resolving.de/urn:isbn:978-91-554-7716-5

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-112345
http://nbn-resolving.de/urn:isbn:978-91-554-7716-5

Similar Items