Reconstitution of the anti-apoptotic bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic bax protein
The anti-apoptotic B-cell CLL/lymphoma-2 (Bcl-2) protein and its counterpart, the pro-apoptotic Bcl-2-associated X protein (Bax), are key players in the regulation of the mitochondrial pathway of apoptosis. However, how they interact at the mitochondrial outer membrane (MOM) and there determine whet...
| Main Authors: | , , , , , |
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| Format: | Others |
| Language: | English |
| Published: |
Umeå universitet, Kemiska institutionen
2013
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-70192 |