Mechanisms involved in amyloid induced cytotoxicity

Amyloidoses comprise a group of diseases where normal or mutated protein precipitates into amyloid fibrils. The deposition of fibrils causes dysfunction of organs and toxicity to nervous tissue. Up to date, 24 different proteins and peptides are known to be able to form amyloid fibrils. The most wel...

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Bibliographic Details
Main Author: Östman, Johan
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Molekylärbiologi (Teknat- och Medfak) 2005
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-541
http://nbn-resolving.de/urn:isbn:91-7305-897-1