The hematopoietic transcription factor RUNX1 : a structural view

The hematopoietic transcription factor RUNX1 : a structural view

The malfunction of the transcriptional regulator RUNX1 is the major cause of several variants of acute human leukemias and its normal function is to regulate the development of the blood system in concert with other transcriptional co-regulators. RUNX1 belongs to a conserved family of heterodimeric...

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Bibliographic Details
Main Author: Bäckström, Stefan
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Umeå centrum för molekylär patogenes (UCMP) 2004
Subjects:
Molecular medicine
RUNX1
Runt domain
CBFβ
transcription factor
leukaemia
protein crystallography
anomalous diffraction
Molekylärmedicin
Molecular medicine (genetics and pathology)
Molekylär medicin (genetik och patologi)
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-192
http://nbn-resolving.de/urn:isbn:91-7305-476-3

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-192
http://nbn-resolving.de/urn:isbn:91-7305-476-3

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