Telomere length - inheritance pattern and role as a biomarker
Telomeres are repetitive TTAGGG structures ending each chromosome and thereby protecting its integrity. Due to the end-replication problem, telomeres shorten with each cell division. When reaching a critical telomere length (TL), the cells stop dividing and enter replicative senescence. It has been...
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| Format: | Doctoral Thesis |
| Language: | English |
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Umeå universitet, Medicinsk biovetenskap
2008
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1844 http://nbn-resolving.de/urn:isbn:978-7264-620-9 |