A Drosophila Disease-Model for Transthyretin-associated Amyloidosis

Amyloidoses comprise a group of gain-of-toxic function protein misfolding diseases, in which normally soluble proteins in their functional state undergo conformational changes into highly organized and generally intractable thread-like aggregates, termed amyloid fibrils. These structures accumulate...

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Bibliographic Details
Main Author: Pokrzywa, Malgorzata
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Molekylärbiologi (Medicinska fakulteten) 2008
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1677
http://nbn-resolving.de/urn:isbn:978-91-7264-579