A Drosophila Disease-Model for Transthyretin-associated Amyloidosis
Amyloidoses comprise a group of gain-of-toxic function protein misfolding diseases, in which normally soluble proteins in their functional state undergo conformational changes into highly organized and generally intractable thread-like aggregates, termed amyloid fibrils. These structures accumulate...
Main Author: | |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
Umeå universitet, Molekylärbiologi (Medicinska fakulteten)
2008
|
Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1677 http://nbn-resolving.de/urn:isbn:978-91-7264-579 |