Membrane Insertion of Marginally Hydrophobic Transmembrane Helices Depends on Sequence Context

Membrane Insertion of Marginally Hydrophobic Transmembrane Helices Depends on Sequence Context

In mammalian cells, most integral membrane proteins are initially inserted into the endoplasmic reticulum membrane by the so-called Sec61 translocon. However, recent predictions suggest that many transmembrane helices (TMHs) in multispanning membrane proteins are not sufficiently hydrophobic to be r...

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Bibliographic Details
Main Authors: Hedin, Linnea E., Öjemalm, Karin, Bernsel, Andreas, Hennerdal, Aron, Illergård, Kristoffer, Enquist, Karl, Kauko, Anni, Cristobal, Susana, von Heijne, Gunnar, Lerch-Bader, Mirjam, Nilsson, Ingmarie, Elofsson, Arne
Format: Others
Language:English
Published: Stockholms universitet, Institutionen för biokemi och biofysik 2010
Subjects:
Biochemistry
Biokemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-33926

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-33926

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