Specificity of antisense oligonucleotide derivatives and cellular delivery by cell-penetrating peptides
Atypical gene expression has a major influence on the disease profile of several severe human disorders. Oligonucleotide (ON) based therapeutics has opened an avenue for compensating deviant protein expression by acting on biologically important nucleic acids, mainly RNAs. Antisense ONs (asONs) can...
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Format: | Doctoral Thesis |
Language: | English |
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Stockholms universitet, Institutionen för neurokemi
2009
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-31226 http://nbn-resolving.de/urn:isbn:978-91-7155-950-0 |