Specificity of antisense oligonucleotide derivatives and cellular delivery by cell-penetrating peptides

Atypical gene expression has a major influence on the disease profile of several severe human disorders. Oligonucleotide (ON) based therapeutics has opened an avenue for compensating deviant protein expression by acting on biologically important nucleic acids, mainly RNAs. Antisense ONs (asONs) can...

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Bibliographic Details
Main Author: Guterstam, Peter
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för neurokemi 2009
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-31226
http://nbn-resolving.de/urn:isbn:978-91-7155-950-0