Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates

This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their rea...

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Bibliographic Details
Main Author: Westberg, Emelie
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för material- och miljökemi (MMK) 2015
Subjects:
PAH
DNA
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-110490
http://nbn-resolving.de/urn:isbn:978-91-7649-074-7