Optimizing purification of oligonucleotides with reversed phase trityl-on solid phase extraction
Oligonucleotides are synthetic strings of DNA or RNA used mostly for biochemical analysis and diagnostics. For them to be useful in these fields, a purity over 90% is most often required. However, when synthesizing these sequences, many “failures” (shorter sequences) are made in the step-wise proces...
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| Format: | Others |
| Language: | English |
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Örebro universitet, Institutionen för naturvetenskap och teknik
2019
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-76844 |