Synthesis of enantiopure building blocks for biologically active compounds by enzyme catalysis. Optimizing reaction conditions for increased enantioselectivity and activity
Efficient methods for synthesis of enantiomerically pure enantiomers of a series of secondary alcohols and butanoates have been performed by kinetic resolution of the racemic alcohols and esters catalyzed by lipase B from Candida antarctica (Novozym 435). The effect of the substrate structure on E w...
Main Author: | |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
Norges teknisk-naturvitenskapelige universitet, Institutt for kjemi
2004
|
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2098 http://nbn-resolving.de/urn:isbn:82-471-6307-1 |