Synthesis of enantiopure building blocks for biologically active compounds by enzyme catalysis. Optimizing reaction conditions for increased enantioselectivity and activity

Efficient methods for synthesis of enantiomerically pure enantiomers of a series of secondary alcohols and butanoates have been performed by kinetic resolution of the racemic alcohols and esters catalyzed by lipase B from Candida antarctica (Novozym 435). The effect of the substrate structure on E w...

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Bibliographic Details
Main Author: Jacobsen, Elisabeth Egholm
Format: Doctoral Thesis
Language:English
Published: Norges teknisk-naturvitenskapelige universitet, Institutt for kjemi 2004
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2098
http://nbn-resolving.de/urn:isbn:82-471-6307-1