Chitosan-based siRNA delivery to rat brain endothelial and glioma cells for optimization of P-glycoprotein knockdown in vitro
The purpose of this thesis was to investigate the transfection efficiencies of chitosan- siRNA nanoparticles in the two rat brain-derived cell lines C6 and RBE4. Furthermore, the main goal was to silence P-glycoprotein (P-gp) expression in these cell lines and to assess the possibility of implementi...
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| Format: | Others |
| Language: | English |
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Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi
2012
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-18376 |