Studies towards a general method for attachment of a nuclear import signal. Stabilization of the m3G-Cap.
A synthetic pathway towards the cap-structure of 2,2,7-trimethylguanosine containing a methylene modified triphosphate bridge have been investigated. The modification to the triphosphate bridge is hoped to slow down cap degradation and give the connected oligunucleotide an increased lifetime. This...
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Format: | Others |
Language: | English |
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Mälardalens högskola, Akademin för hållbar samhälls- och teknikutveckling
2010
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-9728 |